Investigation of lactose intolerance in the elderly
DOI:
https://doi.org/10.18378/rebes.v16i2.12210Keywords:
Lactose Intolerance, Clinical Diagnosis, Health of the ElderlyAbstract
Introduction: lactose intolerance is a prevalent condition in Brazil, affecting approximately 35% of the adult population and being more common among women. This condition, resulting from lactase enzyme deficiency, causes gastrointestinal symptoms such as abdominal pain, flatulence, and diarrhea after the ingestion of dairy products. The diversity of diagnostic and therapeutic approaches raises questions regarding the effectiveness of current practices, especially in the care of older adults. Objective: to investigate the main diagnostic and therapeutic procedures adopted by healthcare professionals in the management of older adults with lactose intolerance, analyzing strategies, difficulties, and perceptions regarding clinical outcomes. Methods: this is a qualitative and descriptive study conducted through semi-structured interviews with healthcare professionals. Data collection was performed using the “snowball” sampling technique, with thematic content analysis based on Minayo’s methodology (2014), using MAXQDA 24 software. Results: the most recurrent themes were gastrointestinal symptoms, the use of lactase enzymes, calcium and vitamin D supplementation, and exclusion and reintroduction diets. Diagnosis was predominantly clinical, complemented by tests such as the lactose tolerance test. Treatment adherence was satisfactory; however, there was initial resistance and economic barriers. Strategies such as replacing dairy products with plant-based foods and the use of A2 casein products were identified as alternatives. Conclusion: healthcare professionals employ different strategies for the diagnosis and treatment of lactose intolerance in older adults, with emphasis on dietary adaptation, enzyme use, and supplementation, despite challenges related to adherence and cost.
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References
BARONE, A.C.C. et al. Intolerância à lactose e má absorção: manifestações clínicas, diagnósticas e tratamento. Brazilian Journal of Implantology and Health Sciences, v. 6, n. 10, p. 707-720. 2024.
CASSELLA, D.G. et al. Lactose Breath test in adults: Are symptoms predictive of lactose malabsorption? Clin Nutr ESPEN, v. 72, 2026.
CASTELLANO, B.F. et al. Intolerância à lactose: diagnóstico clínico laboratorial e genético, v. 80, n. 2, p. 51-53, 2022.
CATANZARO, R.; SCIUTO, M.; MAROTTA, F. Lactose intolerance: An update on pathogenesis, diagnosis, and treatment. Nutrition Research, v. 89, p. 23–34, 2021.
CHENGOLOVA, Z; IVANOVA, R; GABROVSKA K. Lactose intolerance – Single nucleotide polymorphisms and treatment. J Am Nutr Assoc, v. 43, n. 2, p. 213-220, 2024.
CONSTANZO, M. G.; CANANI, R. B. Lactose intolerance: Common misunderstandings. Annals of Nutrition and Metabolism, v. 73, p. 30–37, 2018.
DEWIASTY, E. et al. Prevalence of lactose intolerance and nutrients intake in an older population regarded as lactase non-persistent. Clin Nutr, v. 43, p. 317-321, 2021
DOMÍNGUEZ-JIMÉNEZ, J. L.; FERNÁNDEZ-SUÁREZ, A. Diagnosis of lactose intolerance. Medicina Clínica, v. 148, p. 262–264, 2017.
DOMINICI, S.; DONATI, N.; MENABUE, S.; DI SETFANO, M.; FACIONE, M. S. The impact of lactose intolerance diagnosis: costs, timing, and quality-of-life. Internal and emergency medicine, v. 20, n. 5, p. 1519–1527, 2025.
FASSIO, F.; FACIONI, M. S.; GUAGNINI, F. Lactose maldigestion, malabsorption, and intolerance: A comprehensive review with a focus on current management and future perspectives. Nutrients, v. 10, n. 11, p. 1599, 2018.
GALLO, A. et al. Lactose malabsorption and intolerance: What is the correct management in older adults? Clinical Nutrition, v. 42, n. 12, p. 2540-2545. 2023.
GALLO, A.; MARZETTI, E.; PELLEGRINO, S.; MONTALTO, M. Lactose malabsorption and intolerance in older adults. Current Opinion in Clinical Nutrition & Metabolic Care, v. 27, n. 4, p. 333–337, 2024.
IBRAHIM, S. A. et al. Fermented foods and probiotics: An approach to lactose intolerance. Journal of Dairy Research, v. 88, n. 3, p. 357–365, 2021.
JANSSENDUIJGHUIJSEN, L. et al. Changes in gut microbiota and lactose intolerance symptoms before and after daily lactose supplementation in individuals with the lactase nonpersistent genotype. Am J Clin Nutr, v. 119, n. 3, p. 702-710. 2024.
MALIK, T. F.; PANUGANTI, K. K. Lactose intolerance. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing, 2023.
MINAYO, M. C. de S. O desafio do conhecimento: pesquisa qualitativa em saúde. 14. ed. São Paulo: Hucitec, 2014.
PRATELLI, G. et al. Cow’s milk: A benefit for human health? Omics tools and precision nutrition for lactose intolerance management. Nutrients, v. 16, n. 2, p. 320, 2024.
RATAJCZAK, A. E. et al. Lactose intolerance in patients with inflammatory bowel diseases and dietary management in prevention of osteoporosis. Nutrition, v. 82, p. 111043, 2021.
SZILAGYI, A.; ISHAYEK, N. Lactose intolerance, dairy avoidance, and treatment options. Nutrients, v. 10, n. 12, p. 1994, 2018.
VINUTO, J. A amostragem em bola de neve na pesquisa qualitativa: um debate em aberto. Temáticas, v. 22, n. 44, p. 203–220, 2014.
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